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ac devd cho  (Selleck Chemicals)


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    Selleck Chemicals ac devd cho
    Ac Devd Cho, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 43 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ac+devd+cho/Ac-DEVD-CHO/pm42854924-64-3-11
    Average 93 stars, based on 43 article reviews
    ac devd cho - by Bioz Stars, 2026-11
    93/100 stars

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    other:

    Article Title: Androgen receptors in corticotropin-releasing hormone neurons mediate the sexual dimorphism in restraint-induced thymic atrophy.
    Article Snippet: Ac- DEVD- CHO was purchased from Selleckchem (S7901).

    Article Title: 3A and 2B proteins of SVA play chess game with host restriction factor DDX23 by apoptotic pathway
    Article Snippet: MG132 ( ) (Selleck, S2619), Ac-DEVD-CHO ( ) (Selleck, S7901), Chloroquine ( ) (Selleck, S6999), Z-VDVAD-FMK ( ) (APExBIO, A1922), Z-DEVD-FMK ( ) (Selleck, S7312), Z-VEID-FMK ( ) (APExBIO, A1923), Z-IETD-FMK ( ) (Selleck, S7314), and Z-LEHD-FMK ( ) (Selleck, E7038).

    Article Title: ERα-mediated endoplasmic reticulum stress drives 4-tert-octylphenol-induced cardiac developmental toxicity in zebrafish.
    Article Snippet: 4-tert-Octylphenol (4-t-OP) is a widespread environmental estrogen, yet its developmental cardiotoxicity and underlying mechanisms remain incompletely understood.. Using zebrafish embryos, this study investigated whether estrogen receptor (ER)–mediated endoplasmic reticulum stress (ERS) contributes to 4-t-OP–induced cardiac malformations.. Developmental exposure to 4-t-OP significantly increased the incidence of cardiac abnormalities, accompanied by pericardial edema and reduced heart rate.

    Article Title: Juglone induces GSDME-mediated pyroptosis by targeting HSP90α ATPase domain to promote STAT3 degradation in glioblastoma multiforme.
    Article Snippet: Glioblastoma (GBM) is a highly aggressive primary brain tumor with grim overall median survival, and its therapeutic efficacy is severely limited due to drug resistance.. Therefore, developing effective and safe chemotherapy regimens is urgently required.. Juglone, a natural bioactive constituent derived from traditional Chinese herbs, has emerged as a promising therapeutic agent against various human malignancies.

    Article Title: Activation of human endogenous retroviruses by Sox proteins induces cell apoptosis via the caspase-3 pathway
    Article Snippet: NCCIT, HeLa, and 293T cells were treated with the antiapoptotic drugs Z-DEVD-FMK (10 μM; Selleck Chemicals, TX, USA) and Ac-DEVD-CHO (2 μM; Selleck) for 2 h, after which the medium was replaced with a fresh medium.

    Article Title: Activation of human endogenous retroviruses by Sox proteins induces cell apoptosis via the caspase-3 pathway.
    Article Snippet: NCCIT, HeLa, and 293T cells were treated with the antiapoptotic drugs Z-DEVD-FMK (10 μM; Selleck Chemicals, TX, USA) and Ac-DEVD-CHO (2 μM; Selleck) for 2 h, after which the medium was replaced with a fresh medium.




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    ac devd cho  (MedChemExpress)
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    ( A ) Volcano plot of differentially expressed genes (DEGs) in MFC cells (Control versus DDP + Zn 2+ ). ( B ) KEGG pathway enrichment of DEGs. ( C ) Quantification of extracellular dsDNA. ( D ) JC-1 staining assessed by fluorescence microscopy and flow cytometry. ( E ) γ-H2AX immunofluorescence staining. Scale bar, 20 μm. ( F ) ASC speck colocalization with AIM2, Caspase-1, Caspase-8, and RIPK1. Scale bars, 5 μm (overview) and 1 μm (enlarged). ( G ) Western blot analysis of necroptosis markers (RIPK1, p-RIPK1, MLKL, and p-MLKL) and PANoptosis-related proteins (AIM2 and ZBP1). ( H ) Western blot analysis of apoptosis executors (Caspase-8, Caspase-3, and cleaved forms). ( I ) Western blot analysis of pyroptosis markers (Caspase-1, GSDMD, and cleaved forms). ( J ) Cell viability after DDP + Zn 2+ combined with VX-765, <t>Ac-DEVD-CHO,</t> or Nec-1. ( K ) PANoptosis-related proteins in si AIM2 cells. ( L and M ) cGAS activity (L) and expression (M) under Zn 2+ treatment. ( N ) Violin plot of cGAS expression. ( O ) Western blot analysis of STING pathway (STING, p-STING, TBK1, p-TBK1, IRF3, and p-IRF3). ( P ) CIBERSORT analysis of immune cell infiltration. ( Q ) BMDC maturation (CD80 + CD86 + ) after different treatments. ( R ) Schematic of the DDP + Zn 2+ –induced ICD. Data in (C), (J), and (L) are mean ± SD. Statistical analysis for (C), (J), (L), (N), and (P) used a two-tailed unpaired Student’s t test. (R) was created in BioRender. Fei, G. (2026) https://BioRender.com/8ri399r . * P < 0.05.
    Ac Devd Cho, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ac devd cho  (TargetMol)
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    ( A ) Volcano plot of differentially expressed genes (DEGs) in MFC cells (Control versus DDP + Zn 2+ ). ( B ) KEGG pathway enrichment of DEGs. ( C ) Quantification of extracellular dsDNA. ( D ) JC-1 staining assessed by fluorescence microscopy and flow cytometry. ( E ) γ-H2AX immunofluorescence staining. Scale bar, 20 μm. ( F ) ASC speck colocalization with AIM2, Caspase-1, Caspase-8, and RIPK1. Scale bars, 5 μm (overview) and 1 μm (enlarged). ( G ) Western blot analysis of necroptosis markers (RIPK1, p-RIPK1, MLKL, and p-MLKL) and PANoptosis-related proteins (AIM2 and ZBP1). ( H ) Western blot analysis of apoptosis executors (Caspase-8, Caspase-3, and cleaved forms). ( I ) Western blot analysis of pyroptosis markers (Caspase-1, GSDMD, and cleaved forms). ( J ) Cell viability after DDP + Zn 2+ combined with VX-765, <t>Ac-DEVD-CHO,</t> or Nec-1. ( K ) PANoptosis-related proteins in si AIM2 cells. ( L and M ) cGAS activity (L) and expression (M) under Zn 2+ treatment. ( N ) Violin plot of cGAS expression. ( O ) Western blot analysis of STING pathway (STING, p-STING, TBK1, p-TBK1, IRF3, and p-IRF3). ( P ) CIBERSORT analysis of immune cell infiltration. ( Q ) BMDC maturation (CD80 + CD86 + ) after different treatments. ( R ) Schematic of the DDP + Zn 2+ –induced ICD. Data in (C), (J), and (L) are mean ± SD. Statistical analysis for (C), (J), (L), (N), and (P) used a two-tailed unpaired Student’s t test. (R) was created in BioRender. Fei, G. (2026) https://BioRender.com/8ri399r . * P < 0.05.
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    ac devd cho  (Selleck Chemicals)
    93
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    ( A ) Volcano plot of differentially expressed genes (DEGs) in MFC cells (Control versus DDP + Zn 2+ ). ( B ) KEGG pathway enrichment of DEGs. ( C ) Quantification of extracellular dsDNA. ( D ) JC-1 staining assessed by fluorescence microscopy and flow cytometry. ( E ) γ-H2AX immunofluorescence staining. Scale bar, 20 μm. ( F ) ASC speck colocalization with AIM2, Caspase-1, Caspase-8, and RIPK1. Scale bars, 5 μm (overview) and 1 μm (enlarged). ( G ) Western blot analysis of necroptosis markers (RIPK1, p-RIPK1, MLKL, and p-MLKL) and PANoptosis-related proteins (AIM2 and ZBP1). ( H ) Western blot analysis of apoptosis executors (Caspase-8, Caspase-3, and cleaved forms). ( I ) Western blot analysis of pyroptosis markers (Caspase-1, GSDMD, and cleaved forms). ( J ) Cell viability after DDP + Zn 2+ combined with VX-765, <t>Ac-DEVD-CHO,</t> or Nec-1. ( K ) PANoptosis-related proteins in si AIM2 cells. ( L and M ) cGAS activity (L) and expression (M) under Zn 2+ treatment. ( N ) Violin plot of cGAS expression. ( O ) Western blot analysis of STING pathway (STING, p-STING, TBK1, p-TBK1, IRF3, and p-IRF3). ( P ) CIBERSORT analysis of immune cell infiltration. ( Q ) BMDC maturation (CD80 + CD86 + ) after different treatments. ( R ) Schematic of the DDP + Zn 2+ –induced ICD. Data in (C), (J), and (L) are mean ± SD. Statistical analysis for (C), (J), (L), (N), and (P) used a two-tailed unpaired Student’s t test. (R) was created in BioRender. Fei, G. (2026) https://BioRender.com/8ri399r . * P < 0.05.
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    Average 93 stars, based on 1 article reviews
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    caspase 3  (Beyotime)
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    ( A ) Volcano plot of differentially expressed genes (DEGs) in MFC cells (Control versus DDP + Zn 2+ ). ( B ) KEGG pathway enrichment of DEGs. ( C ) Quantification of extracellular dsDNA. ( D ) JC-1 staining assessed by fluorescence microscopy and flow cytometry. ( E ) γ-H2AX immunofluorescence staining. Scale bar, 20 μm. ( F ) ASC speck colocalization with AIM2, Caspase-1, Caspase-8, and RIPK1. Scale bars, 5 μm (overview) and 1 μm (enlarged). ( G ) Western blot analysis of necroptosis markers (RIPK1, p-RIPK1, MLKL, and p-MLKL) and PANoptosis-related proteins (AIM2 and ZBP1). ( H ) Western blot analysis of apoptosis executors (Caspase-8, Caspase-3, and cleaved forms). ( I ) Western blot analysis of pyroptosis markers (Caspase-1, GSDMD, and cleaved forms). ( J ) Cell viability after DDP + Zn 2+ combined with VX-765, <t>Ac-DEVD-CHO,</t> or Nec-1. ( K ) PANoptosis-related proteins in si AIM2 cells. ( L and M ) cGAS activity (L) and expression (M) under Zn 2+ treatment. ( N ) Violin plot of cGAS expression. ( O ) Western blot analysis of STING pathway (STING, p-STING, TBK1, p-TBK1, IRF3, and p-IRF3). ( P ) CIBERSORT analysis of immune cell infiltration. ( Q ) BMDC maturation (CD80 + CD86 + ) after different treatments. ( R ) Schematic of the DDP + Zn 2+ –induced ICD. Data in (C), (J), and (L) are mean ± SD. Statistical analysis for (C), (J), (L), (N), and (P) used a two-tailed unpaired Student’s t test. (R) was created in BioRender. Fei, G. (2026) https://BioRender.com/8ri399r . * P < 0.05.
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    ac devd cho  (Beyotime)
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    Effects of BHJ on the expression and activity of apototic-related proteins in HepG2 cells. A Western blot analysis of apoptotic-associated protein levels in HepG2 cells; B , C Effect of BHJ on caspase 9, caspase 3 enzyme activities in HepG2 cells; D Inhibition of BHJ-induced apoptosis by caspase 9 and caspase 3 inhibitors in HepG2 cells. The values are expressed as means ± SD of triplicates tests. * P < 0.05 comparison between the absence and presence of inhibitor in the treatment group
    Ac Devd Cho, supplied by Beyotime, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ac-devd-cho  (MedChemExpress)
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    Effects of BHJ on the expression and activity of apototic-related proteins in HepG2 cells. A Western blot analysis of apoptotic-associated protein levels in HepG2 cells; B , C Effect of BHJ on caspase 9, caspase 3 enzyme activities in HepG2 cells; D Inhibition of BHJ-induced apoptosis by caspase 9 and caspase 3 inhibitors in HepG2 cells. The values are expressed as means ± SD of triplicates tests. * P < 0.05 comparison between the absence and presence of inhibitor in the treatment group
    Ac Devd Cho, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    caspase 3 inhibitor ac devd cho  (MedChemExpress)
    95
    MedChemExpress caspase 3 inhibitor ac devd cho
    Effects of BHJ on the expression and activity of apototic-related proteins in HepG2 cells. A Western blot analysis of apoptotic-associated protein levels in HepG2 cells; B , C Effect of BHJ on caspase 9, caspase 3 enzyme activities in HepG2 cells; D Inhibition of BHJ-induced apoptosis by caspase 9 and caspase 3 inhibitors in HepG2 cells. The values are expressed as means ± SD of triplicates tests. * P < 0.05 comparison between the absence and presence of inhibitor in the treatment group
    Caspase 3 Inhibitor Ac Devd Cho, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ac+devd+cho/Ac-DEVD-CHO/pm42397844-66-1-14
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    pf b1077  (MedChemExpress)
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    MedChemExpress pf b1077
    Effects of BHJ on the expression and activity of apototic-related proteins in HepG2 cells. A Western blot analysis of apoptotic-associated protein levels in HepG2 cells; B , C Effect of BHJ on caspase 9, caspase 3 enzyme activities in HepG2 cells; D Inhibition of BHJ-induced apoptosis by caspase 9 and caspase 3 inhibitors in HepG2 cells. The values are expressed as means ± SD of triplicates tests. * P < 0.05 comparison between the absence and presence of inhibitor in the treatment group
    Pf B1077, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ac+devd+cho/Ac-DEVD-CHO/pm42396980-187-4-24
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    hy b0069 ac devd cho mce  (MedChemExpress)
    97
    MedChemExpress hy b0069 ac devd cho mce
    Effects of BHJ on the expression and activity of apototic-related proteins in HepG2 cells. A Western blot analysis of apoptotic-associated protein levels in HepG2 cells; B , C Effect of BHJ on caspase 9, caspase 3 enzyme activities in HepG2 cells; D Inhibition of BHJ-induced apoptosis by caspase 9 and caspase 3 inhibitors in HepG2 cells. The values are expressed as means ± SD of triplicates tests. * P < 0.05 comparison between the absence and presence of inhibitor in the treatment group
    Hy B0069 Ac Devd Cho Mce, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ( A ) Volcano plot of differentially expressed genes (DEGs) in MFC cells (Control versus DDP + Zn 2+ ). ( B ) KEGG pathway enrichment of DEGs. ( C ) Quantification of extracellular dsDNA. ( D ) JC-1 staining assessed by fluorescence microscopy and flow cytometry. ( E ) γ-H2AX immunofluorescence staining. Scale bar, 20 μm. ( F ) ASC speck colocalization with AIM2, Caspase-1, Caspase-8, and RIPK1. Scale bars, 5 μm (overview) and 1 μm (enlarged). ( G ) Western blot analysis of necroptosis markers (RIPK1, p-RIPK1, MLKL, and p-MLKL) and PANoptosis-related proteins (AIM2 and ZBP1). ( H ) Western blot analysis of apoptosis executors (Caspase-8, Caspase-3, and cleaved forms). ( I ) Western blot analysis of pyroptosis markers (Caspase-1, GSDMD, and cleaved forms). ( J ) Cell viability after DDP + Zn 2+ combined with VX-765, Ac-DEVD-CHO, or Nec-1. ( K ) PANoptosis-related proteins in si AIM2 cells. ( L and M ) cGAS activity (L) and expression (M) under Zn 2+ treatment. ( N ) Violin plot of cGAS expression. ( O ) Western blot analysis of STING pathway (STING, p-STING, TBK1, p-TBK1, IRF3, and p-IRF3). ( P ) CIBERSORT analysis of immune cell infiltration. ( Q ) BMDC maturation (CD80 + CD86 + ) after different treatments. ( R ) Schematic of the DDP + Zn 2+ –induced ICD. Data in (C), (J), and (L) are mean ± SD. Statistical analysis for (C), (J), (L), (N), and (P) used a two-tailed unpaired Student’s t test. (R) was created in BioRender. Fei, G. (2026) https://BioRender.com/8ri399r . * P < 0.05.

    Journal: Science Advances

    Article Title: Chemo-metallo nanodrivers for spatiotemporally controlled in situ vaccination

    doi: 10.1126/sciadv.aee4577

    Figure Lengend Snippet: ( A ) Volcano plot of differentially expressed genes (DEGs) in MFC cells (Control versus DDP + Zn 2+ ). ( B ) KEGG pathway enrichment of DEGs. ( C ) Quantification of extracellular dsDNA. ( D ) JC-1 staining assessed by fluorescence microscopy and flow cytometry. ( E ) γ-H2AX immunofluorescence staining. Scale bar, 20 μm. ( F ) ASC speck colocalization with AIM2, Caspase-1, Caspase-8, and RIPK1. Scale bars, 5 μm (overview) and 1 μm (enlarged). ( G ) Western blot analysis of necroptosis markers (RIPK1, p-RIPK1, MLKL, and p-MLKL) and PANoptosis-related proteins (AIM2 and ZBP1). ( H ) Western blot analysis of apoptosis executors (Caspase-8, Caspase-3, and cleaved forms). ( I ) Western blot analysis of pyroptosis markers (Caspase-1, GSDMD, and cleaved forms). ( J ) Cell viability after DDP + Zn 2+ combined with VX-765, Ac-DEVD-CHO, or Nec-1. ( K ) PANoptosis-related proteins in si AIM2 cells. ( L and M ) cGAS activity (L) and expression (M) under Zn 2+ treatment. ( N ) Violin plot of cGAS expression. ( O ) Western blot analysis of STING pathway (STING, p-STING, TBK1, p-TBK1, IRF3, and p-IRF3). ( P ) CIBERSORT analysis of immune cell infiltration. ( Q ) BMDC maturation (CD80 + CD86 + ) after different treatments. ( R ) Schematic of the DDP + Zn 2+ –induced ICD. Data in (C), (J), and (L) are mean ± SD. Statistical analysis for (C), (J), (L), (N), and (P) used a two-tailed unpaired Student’s t test. (R) was created in BioRender. Fei, G. (2026) https://BioRender.com/8ri399r . * P < 0.05.

    Article Snippet: The pharmacological inhibitors VX-765, Ac-DEVD-CHO, and Nec-1 were purchased from MedChemExpress (USA).

    Techniques: Control, Staining, Fluorescence, Microscopy, Flow Cytometry, Immunofluorescence, Western Blot, Analysis, Activity Assay, Expressing, Immune Cell, Two Tailed Test

    Effects of BHJ on the expression and activity of apototic-related proteins in HepG2 cells. A Western blot analysis of apoptotic-associated protein levels in HepG2 cells; B , C Effect of BHJ on caspase 9, caspase 3 enzyme activities in HepG2 cells; D Inhibition of BHJ-induced apoptosis by caspase 9 and caspase 3 inhibitors in HepG2 cells. The values are expressed as means ± SD of triplicates tests. * P < 0.05 comparison between the absence and presence of inhibitor in the treatment group

    Journal: BMC Complementary Medicine and Therapies

    Article Title: Antioxidant activity and cytotoxic effects of Benincasa hispida juice on HepG2 cells

    doi: 10.1186/s12906-026-05475-3

    Figure Lengend Snippet: Effects of BHJ on the expression and activity of apototic-related proteins in HepG2 cells. A Western blot analysis of apoptotic-associated protein levels in HepG2 cells; B , C Effect of BHJ on caspase 9, caspase 3 enzyme activities in HepG2 cells; D Inhibition of BHJ-induced apoptosis by caspase 9 and caspase 3 inhibitors in HepG2 cells. The values are expressed as means ± SD of triplicates tests. * P < 0.05 comparison between the absence and presence of inhibitor in the treatment group

    Article Snippet: To test the activity of caspase 3 and caspase 9, 10 μM of Z-LEHD-FMK (BioVision, CA, USA) or 20 μM Ac-DEVD-CHO (Beyotime, Haimen, China) were added and incubated for 2 h prior to addition of BHJ for 48 h, then cell viability was detected by alamar blue assay.

    Techniques: Expressing, Activity Assay, Western Blot, Analysis, Inhibition, Comparison